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  PERSONAL DETAILS

Name             Bruce Douglas George
Address          32a Blandford Avenue, Oxford, OX2 8JL.
Telephone:     01865 316516
Date of birth   1st June 1960.
Status             Married, four children.
Nationality      British

  EDUCATION:

King Edward VI School, Norwich (1970-1978).
St. Bartholomew's Hospital Medical College (1978-1984)

  QUALIFICATIONS:

1981         BSc [Biochemistry]
1984         MB BS
1988         FRCS [England]
1988         FRCS [Edinburgh]
1992         MS
1995         FRCS [Gen]
1997         CCST

  PRIZES:

1986         Bentley Prize

1992         Moynihan Prize of The Association of Surgeons of Great Britain and Ireland

1994         Arris and Gale Lectureship

  PREVIOUS APPOINTMENTS

August 84-January 85
House Physician to Dr D.V.Doyle
Consultant Physician, Whipps Cross Hospital.

February 85-April 85
House Surgeon to Mr W.F.Hendry and Mr H.N.Whitfield
Department of Urology, St. Bartholomew's Hospital.

May 85-July 85
House Surgeon to Mr O.J.A.Gilmore
Consultant Surgeon, St. Bartholomew's Hospital.

August 85-July 86
SHO in Department of Pathology, St. Bartholomew's Hospital.

August 86-January 87
SHO to Dr E.Glucksman
Department of Accident and Emergency, King's College Hospital.

St. Bartholomew's Hospital SHO Rotation

February 87-July 87
SHO in Paediatric Surgery
Hospital for Sick Children, Great Ormond Street.

August 87-January 88
SHO to Mr J.M.Wellwood
Consultant Surgeon, Whipps Cross Hospital.

February 88-July 88
SHO in Orthopaedics, Homerton Hospital.

August 88-December 88
SHO to Professor R.F.M.Wood, Professor J.S.P.Lumley and Mr R.K.S.Phillips
Professorial Surgical Unit, St. Bartholomew's Hospital.

Registrar Rotation, Southend General Hospital

January 89-May 89
Registrar to Mr B.S.Ashby
Consultant Surgeon, Southend General Hospital.

June 89-November 89
Registrar to Mr A.A.Brown Consultant Surgeon and to Mr A.J.Ball, Consultant Urologist, Southend General Hospital.

November 89-February 90
Registrar to Mr C.C.Ware
Consultant Surgeon, Southend General Hospital

Research Fellow, Royal London Hospital

February 90-May 91
Medical Research Council Research Fellow under direction of Professor N.S.Williams
Royal London Hospital

Post-research Registrar Experience

May 91-June 92
Lecturer/Registrar to Professor N.S.Williams
Surgical Unit, Royal London Hospital.

July 92-March 1993
Registrar to Professor N.S.Williams, Mr A.W.Goode and Mr O.J.McAnena
Royal London Hospital.

April 93-August 1993
Locum Senior Registrar to Mr R.J.Earlam and Mr F.W.Cross
Royal London Hospital.

Senior Registrar Rotation

Sept 1993-February 1994
Senior Registrar to Mr B.J.Britton and Mr M.J.Greenall
John Radcliffe Hospital, Oxford.

March 1994-August 1994
Senior Registrar to Mr T.C.B.Dehn and Mr S.P.Courtney
Royal Berkshire Hospital, Reading.

September 1994-Feb 1995
Senior Registrar to Mr D.P.Goodwin and Mr R.B.Galland
Royal Berkshire Hospital, Reading.

March 1995-February 1996
Senior Registrar to Mr N.J.McC.Mortensen and Mr N.E.Dudley.
John Radcliffe Hospital, Oxford.

March 1996-December 1996
Senior Registrar to Mr M.Kettlewell and Miss P.J.Clarke
John Radcliffe Hospital, Oxford.

Other Colorectal Experience

January 1997-February 1997
Visiting Fellow, Service de Professeur Roland Parc
Centre de Chirurgie Digestive
Hopital St Antoine, Paris.

Locum Consultant

February 1997-June 1997
Locum Consultant Surgeon
John Radcliffe Hospital, Oxford.

Current Appointment
Consultant Colorectal Surgeon
John Radcliffe Hospital, Oxford.

  MEMBERSHIP OF PROFESSIONAL ORGANISATIONS

- General Medical Council
- Medical Defence Union
- Association of Coloproctology of Great Britain And Ireland

  PUBLICATIONS

Chapters in Books

Faecal Incontinence.
George BD and Williams NS.
In: Taylor and Johnson: Recent Advances in Surgery 16.

The anal sphincter in incontinence.
Hallan RI, George BD and Williams NS.
In: Nyhus, Appleton and Lange: Surgery Annual 1993: 25 part 2, 85-115..

Rehabilitation of Faecal Incontinence.
Hallan RI, George BD and Williams NS.
In: Illis: Neurological Rehabilitation 1994: 382-393.

The Acute Abdomen.
George BD and Campbell R.
In: Skinner, Swain, Peyton and Robertson: Cambridge Textbook of Accident and Emergency Medicine 1997: 951-969.

Anal and Perianal Diseases
B D George
In: Gastroenterolgy. Medicine. September 1998 and February 2003.

Diverticular disease: diverticulitis, bleeding and fistula.
B D George
Oxford Textbook of Surgery, 2nd edition 2001

Angiodysplasia
B D George
Oxford Textbook of Surgery, 2nd edition 2001.

Inflammatory Bowel Disease
  1. Delayed surgery for acute severe colitis is associated with increased risk of postoperative complications.
    Randall J, Singh B, Warren BF, Travis SP, Mortensen NJ, George BD.
    Br J Surg. 2010 Mar;97(3):404-9.

  2. Is Clostridium difficile infection a particular problem after reversal of ileostomy?
    Randall JK, Young BC, Patel G, Fitzgerald A, George BD.
    Colorectal Dis. 2011 Mar;13(3):308-11. doi: 10.1111/j.1463-1318.2009.02139.x.

  3. The pattern and outcome of acute severe colitis.
    Dinesen LC, Walsh AJ, Protic MN, Heap G, Cummings F, Warren BF, George B, Mortensen NJ, Travis SP.
    J Crohns Colitis. 2010 Oct;4(4):431-7. Epub 2010 Feb 19.

  4. Perianal Crohn's disease. Singh B, Mortensen NJ, Jewell DP and George BD. Br. J. Surg. 2004: 91; 801-14.

  5. Fearnhead NS, Chowdhury R, Box B, George BD, Jewell DP, Mortensen NJ. Long-term follow-up of strictureplasty for Crohn's disease. Br J Surg. 2006 Apr;93(4):475-82.

  6. Hyder SA, Travis SP, Jewell DP, McC Mortensen NJ, George BD. Fistulating anal Crohn's disease: results of combined surgical and infliximab treatment. Dis Colon Rectum. 2006 Dec;49(12):1837-41.

  7. Diversion colitis-new light through old windows.
    Edwards CM, George BD and Warren BF.
    Histopathology 1999: 34; 1-5.

  8. Connective tissue changes in ileal Crohn's disease- relationship to disease phenotype and ulcer associated cell lineage.
    Borley NR, Mortensen NJMc, Kettlewell MGW, George BD, Jewell DP and Warren BF.
    Dis Colon Rectum 2001 44; 388-96.

  9. The role of a defunctioning stoma in the management of large bowel Crohn's disease.
    Edwards C, George B, Jewell DP, Warren BF, Mortensen N and Kettlewell M.
    Br. J. Surg. 2000 87; 1063-6

  10. Impotence after mesorectal and close rectal dissection for inflammatory bowel disease.
    Lindsey I, George BD, Kettlewell MGW and Mortensen NJMcC.
    Dis Colon Rectum 2001: 44; 831-5.

  11. Randomised, double-blind, placebo-controlled trial of sildenafil (Viagra) for erectile dysfunction after rectal excision for cancer and inflammatory bowel disease.
    Lindsey I, George B, Kettlewell M and Mortensen N.
    Dis Colon Rectum 2002: 45: 727-32.

  12. Recurrence after abdominal surgery for Crohn's disease: relationship to disease site and surgical procedure.
    Borley NR, Mortensen NJ, Chaudrey MA, Mohammed S, Warren BF, George BD, Clark T, Jewell DP and Kettlewell MG.
    Dis Colon Rect 2002 45: 377-83

Colorectal Cancer
  1. Changes in the management and outcome of rectal cancer over a 10-year period in Oxford.
    Chambers W, Hancock L, McKenzie R, Buchel O, Lindsey I, Cunningham C, George B, Mortensen N.
    Colorectal Dis. 2011 Sep;13(9):1004-8. doi: 10.1111/j.1463-1318.2010.02360.x. Epub 2010 Jul 1.

  2. A case-control study of colorectal cancer detection by quantification of DNA isolated from directly collected exfoliated colonocytes.
    Loktionov A, Ferrett CG, Gibson JJ, Bandaletova T, Dion C, Llewelyn AH, Lywood HG, Lywood RC, George BD, Mortensen NJ.
    Int J Cancer. 2010 Apr 15;126(8):1910-9.

  3. Examination of outcome following abdominoperineal resection for adenocarcinoma in Oxford.
    Chambers W, Khan A, Waters R, Lindsey I, George B, Mortensen N, Cunningham C.
    Colorectal Dis. 2010 Dec;12(12):1192-7. doi: 10.1111/j.1463-1318.2009.01939.x.

  4. Examination of outcome following abdominoperineal resection for adenocarcinoma in Oxford.
    Chambers W, Khan A, Waters R, Lindsey I, George B, Mortensen N, Cunningham C.
    Colorectal Dis. 2010 Dec;12(12):1192-7. doi: 10.1111/j.1463-1318.2009.01939.x.

Major papers or trials
  1. Development of an electrically stimulated gracilis neoanal sphincter.
    Williams NS, Patel J, George BD, Hallan RI and Watkins ES.
    Lancet 1991: 338 1166-1169.

  2. Physiological and Histochemical Adaptation of the Electrically Stimulated Gracilis Muscle to Neoanal sphincter function.
    George BD, Williams NS, Patel J, Swash M and Watkins ES.
    British Journal of Surgery 1993: 80; 1342-46.

  3. The Electrically Stimulated Gracilis Neosphincter Incorporated as part of Total Anorectal Reconstruction following Abdominoperineal Excision of the Rectum.
    Mander BJ, Abercrombie JF, George BD and Williams NS.
    Annals of Surgery 1996: 224; 702-711.

  4. Randomised, double-blind, placebo-controlled trial of sildenafil (Viagra) for erectile dysfunction after rectal excision for cancer and inflammatory bowel disease.
    Lindsey I, George B, Kettlewell M and Mortensen N.
    Dis Colon Rectum 2002: 45: 727-32.

  5. A randomised controlled trial of fibrin glue vs. conventional treatment for anal fistula.
    Lindsey I, Smilgin-Humphreys MM, Cunningham C, Mortensen NJ and George BD.
    Dis Colon Rectum 2002: 45; 1608-15.

Miscellaneous
  1. A rare cause of an ileocaecal mass and lymphadenopathy.
    Culver EL, Barnes E, Delaney D, Ellis AJ, George B, Chapman RW.
    Gut. 2011 Sep 3. [Epub ahead of print]

  2. Use of topical negative pressure in assisted abdominal closure does not lead to high incidence of enteric fistulae.
    Guy R, George B.
    Colorectal Dis. 2011 Jan;13(1):108-9. doi: 10.1111/j.1463-1318.2010.02444.x.

  3. Jones OM, Ramalingam T, Merrie A, Cunningham C, George BD, Mortensen NJ, Lindsey I.
    Randomized clinical trial of botulinum toxin plus glyceryl trinitrate vs. botulinum toxin alone for medically resistant chronic anal fissure: overall poor healing rates.
    Dis Colon Rectum. 2006 Oct;49(10):1574-80.

  4. Histopathology of stapled haemorrhoidectomy specimens: a cautionary note.
    George BD, Shetty D, Lindsey I, Mortensen N and Warren BF.
    Colorectal Dis 2002; 4.

Papers

Bretagnol F, Rullier E, George B, Warren BF, Mortensen NJ.
Local Therapy for Rectal Cancer: Still Controversial?
Dis Colon Rectum. 2007 Feb 7;

Jones OM, Ramalingam T, Merrie A, Cunningham C, George BD, Mortensen NJ, Lindsey I.
Randomized clinical trial of botulinum toxin plus glyceryl trinitrate vs. botulinum toxin alone for medically resistant chronic anal fissure: overall poor healing rates.
Dis Colon Rectum. 2006 Oct;49(10):1574-80.

Fearnhead NS, Chowdhury R, Box B, George BD, Jewell DP, Mortensen NJ.
Long-term follow-up of strictureplasty for Crohn's disease.
Br J Surg. 2006 Apr;93(4):475-82.

Box B, Lindsey I, Wheeler JM, Warren BF, Cunningham C, George BD, Mortensen NJ, Jones AC.
Neoadjuvant therapy for rectal cancer: improved tumor response, local recurrence, and overall survival in nonanemic patients.
Dis Colon Rectum. 2005 Jun;48(6):1153-60.

Jones OM, Ramalingam T, Lindsey I, Cunningham C, George BD, Mortensen NJ.
Digital rectal examination of sphincter pressures in chronic anal fissure is unreliable.
Dis Colon Rectum. 2005 Feb;48(2):349-52.

Wheeler JM, Dodds E, Warren BF, Cunningham C, George BD, Jones AC, Mortensen NJ.
Preoperative chemoradiotherapy and total mesorectal excision surgery for locally advanced rectal cancer: correlation with rectal cancer regression grade.
Dis Colon Rectum. 2004 Dec;47(12):2025-31.

Hyder SA, Travis SP, Jewell DP, McC Mortensen NJ, George BD.
Fistulating anal Crohn's disease: results of combined surgical and infliximab treatment.
Dis Colon Rectum. 2006 Dec;49(12):1837-41.

Malignant cysts in the male breast.
Stebbings W, George BD, Boyle S, Plowman PN and Gilmore OJA.
Postgraduate Medical Journal 1987: 63 985-7.

Histopathology of benign non-palpable mammographic lesions.
Barnard N, George BD, Tucker AK and Gilmore OJA.
Journal of Clinical Pathology 1988: 41 26-30.

Development of an electrically stimulated gracilis neoanal sphincter.
Williams NS, Patel J, George BD, Hallan RI and Watkins ES.
Lancet 1991: 338 1166-1169.

Electrically Stimulated Gracilis Neoanal Sphincter.
George BD and Williams NS.
Seminars in Colon and Rectal Surgery 1992: 3 104-9.

Long head of biceps femoris: anatomical basis for its possible use in the construction of an electrically stimulated neoanal sphincter.
Shanahan D, George BD, Riches D, Sinnatamby CS and Williams NS.
Plastic and Reconstructive Surgery 1993: 92;55-8

Perianal abscesses in Children.
Abercrombie JF and George BD.
Annals of Royal College of Surgeons of England 1992: 74 385-6.

Transcranial revascularisation in Children.
George BD, Neville BGR and Lumley JSP.
Developmental Medicine and Child Neurology 1993: 35; 675-82..

Physiological and Histochemical Adaptation of the Electrically Stimulated Gracilis Muscle to Neoanal sphincter function.
George BD, Williams NS, Patel J, Swash M and Watkins ES.
British Journal of Surgery 1993: 80; 1342-46.

Endometrial Stromal Sarcoma of the Rectum.
George BD and Abercrombie JF.
Journal of Obstetrics and Gynaecology 1996:16 (6), 571-2.

The Electrically Stimulated Gracilis Neosphincter Incorporated as part of Total Anorectal Reconstruction following Abdominoperineal Excision of the Rectum.
Mander BJ, Abercrombie JF, George BD and Williams NS.
Annals of Surgery 1996: 224; 702-711..

The Consent Form Signature: a useful clinical sign?
George BD and Toms A.
Annals of Roy Coll Surg Eng 1997: 79; 149-50.

Protocol Violation in Deep Vein Thrombosis Prophylaxis.
George BD, Franklin I, Cook T, Nethercliff J and Galland RB.
Annals of The Royal College of Surgeons of England (in press).

Severe ulcerative colitis associated with complicated diverticular disease.
George BD, Warren BF, DP Jewell and Kettlewell MGW.
Illustrated Case Reports in Gastroenterology (in press).

Multiple pathologies in one appendix.
Sen A, George BD, Warren BF and Mortensen NJMcC.
Illustrated Case Reports in Gastroenterology (in press).

Anal ultrasound predicts the response to non-operative treatment of fecal incontinence in the male
Chen H, Smilgin-Humphreys M, Mortensen N, Kettlewell M, Bulkley GB and George BD.
Annals of Surgery 1999 229: 739-744.

Diversion colitis-new light through old windows.
Edwards CM, George BD and Warren BF.
Histopathology 1999: 34; 1-5.

Surgical Options in the treatment of Severe Chronic Constipation
Romero-Simo M, Mortensen NJMc, Thomson-Fawcett M, George B and Smilgin-Humphreys MM.
Cir. Esp 1999; 65; 201-207.

Connective tissue changes in ileal Crohn's disease- relationship to disease phenotype and ulcer associated cell lineage.
Borley NR, Mortensen NJMc, Kettlewell MGW, George BD, Jewell DP and Warren BF.
Dis Colon Rectum 2001 44; 388-96.

The role of a defunctioning stoma in the management of large bowel Crohn's disease.
Edwards C, George B, Jewell DP, Warren BF, Mortensen N and Kettlewell M.
Br. J. Surg. 2000 87; 1063-6

Chen H, George BD, Kaufman HS, Malaki MB, Mortensen NJ and Kettlewell MG.
Endoscopic transanal resection provides palliation equivalent to transabdominal resection in patients with metastatic rectal cancer.
J Gastrointest Surg 2001 5: 282-6.

Percutaneous endoscopic gastrostomy at the time of tumour resection in advanced oral cancer.
Cunliffe DR, Swanton C, White C, Watt-Smith SR, Cook TA and George BD.
Oral Oncology 2000: 36 ; 471-3.

Histopathology of stapled haemorrhoidectomy specimens: a cautionary note.
George BD, Shetty D, Lindsey I, Mortensen N and Warren BF.
Colorectal Dis 2002; 4.

Impotence after mesorectal and close rectal dissection for inflammatory bowel disease.
Lindsey I, George BD, Kettlewell MGW and Mortensen NJMcC.
Dis Colon Rectum 2001: 44; 831-5.

Lessons from laparoscopic surgery- a fresh look at post-operative management afteajor colorectal procedures.
Lindsey I, George BD, Mortensen NJMcC.
Colorectal Dis. 2001; 3; 107-114.

Randomised, double-blind, placebo-controlled trial of sildenafil (Viagra) for erectile dysfunction after rectal excision for cancer and inflammatory bowel disease.
Lindsey I, George B, Kettlewell M and Mortensen N.
Dis Colon Rectum 2002: 45: 727-32.

Recurrence after abdominal surgery for Crohn's disease: relationship to disease site and surgical procedure.
Borley NR, Mortensen NJ, Chaudrey MA, Mohammed S, Warren BF, George BD, Clark T, Jewell DP and Kettlewell MG.
Dis Colon Rect 2002 45: 377-83

Wheeler JM, Warren BF, Mortensen, Ekanyaka N, Kulacoglu H, Jones AC, George BD and Kettlewell MG.
Quantification of histologic regression of rectal cancer after irradiation: a proposal for a modified staging system.
Dis Colon Rectum 2002: 45; 1051-6.

A randomised controlled trial of fibrin glue vs. conventional treatment for anal fistula.
Lindsey I, Smilgin-Humphreys MM, Cunningham C, Mortensen NJ and George BD.
Dis Colon Rectum 2002: 45; 1608-15.

The role of anal ultrasound in the management of anal fistulas
Lindsey I, Humphreys MM, George BD and Mortensen NJMC.
Colorectal Dis 2002: 4; 118-122.

Nocternal penile tumescence is diminished but not ablated in postproctectomy impotence.
Lindsey I, Cunningham C, George BD, Mortensen NJ.
Dis Colon Rectum 2003: 46; 14-19.

Botulinum toxin as second-line therapy for chronic anal fissure failing 0.2% glyceryl trinitrate.
Lindsey I, Jones OM, Cunningham, George BD, Mortensen.
Dis Colon Rectum 2003: 46; 361-6.

Perianal Crohn's disease.
Singh B, Mortensen NJ, Jewell DP and George BD.
Br. J. Surg. 2004: 91; 801-14.

Correspondence

Electrical stimulation of the gracilis neosphincter.
Williams NS, Patel J, George BD and Watkins ES.
International J. Colorectal Diseases 1991: 6 63-64.


Electrically stimulated gracilis sphincter for bladder incontinence.
Williams NS, Fowler CG, George BD, Blandy JP, Badenoch DF and Patel J.
Lancet 1993: 341; 115-6.

Chapters in Books

Faecal Incontinence.
George BD and Williams NS.
In: Taylor and Johnson: Recent Advances in Surgery 16.

The anal sphincter in incontinence.
Hallan RI, George BD and Williams NS.
In: Nyhus, Appleton and Lange: Surgery Annual 1993: 25 part 2, 85-115..

Rehabilitation of Faecal Incontinence.
Hallan RI, George BD and Williams NS.
In: Illis: Neurological Rehabilitation 1994: 382-393.

The Acute Abdomen.
George BD and Campbell R.
In: Skinner, Swain, Peyton and Robertson: Cambridge Textbook of Accident and Emergency Medicine 1997: 951-969.

Anal and Perianal Diseases
B D George
In: Gastroenterolgy. Medicine. September 1998 and February 2003.

Diverticular disease: diverticulitis, bleeding and fistula.
B D George
Oxford Textbook of Surgery, 2nd edition 2001

Angiodysplasia
B D George
Oxford Textbook of Surgery, 2nd edition 2001.

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